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Joint Replacement
Glucosamine and Chondroitin: Do They Work? Print E-mail
If you have arthritis, you've probably heard of glucosamine and chondroitin. Just about any pharmacy, health food store or grocery store stocks these supplements, which are aimed at people with achy joints. Do they work? What are the risks? These are important questions since alternatives to traditional medications could help people with sensitive stomachs or bad reactions to aspirin, ibuprofen and other osteoarthritis medicines.

A few years ago there was more hype than hard data to support the use of these products. It is important for those with arthritis to research any pain relief product before using it, including talking with their physician.

Recent research shows glucosamine and/or chondroitin may play a useful role in the management of mild osteoarthritis for some people. Note these products are marketed to people with osteoarthritis and not rheumatoid arthritis.

Do they work?
An important study published in Archives of Internal Medicine (July 14, 2003) showed that glucosamine and chondroitin improved symptoms of osteoarthritis and also improved joint mobility for one in five patients studied. A separate study suggests glucosamine may actually slow the progression of osteoarthritis in the knee (The Lancet, January 24, 2001). The study found that patients who took glucosamine experienced far less deterioration and joint pain than those who did not.

Important Considerations

  • Glucosamine is available in the U.S. only as an over-the-counter food supplement. The Food and Drug Administration does not regulate glucosamine the way it does medicines.
  • Supplements may need to be taken for more than two months for full effect.
  • When comparing prices, do so based on the cost per daily dosage. Don't rely solely on the number of pills in a bottle.
  • Always consult your physician before taking any new supplements or medications.

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